Which Practice Area is about managing uncertainties that may have negative or positive impacts on achieving objectives?

The correct choice focuses on "Risk and opportunity management," which is a practice area that specifically addresses the processes involved in identifying, assessing, and managing uncertainties that can affect an organization's ability to achieve its objectives. This practice area emphasizes that uncertainties can have both negative effects (risks) and positive effects (opportunities), and it guides organizations in implementing strategies to minimize threats while maximizing potential benefits.

In risk and opportunity management, organizations assess potential risks that could hinder progress or lead to failure and simultaneously identify opportunities that could enhance performance or provide competitive advantages. This dual focus ensures that organizations are not only reacting to potential problems but are also proactive in leveraging favorable conditions to achieve their goals.

Other practice areas listed do not primarily focus on managing uncertainties in the same comprehensive manner. Business analysis generally pertains to understanding business needs and solutions rather than direct management of risks and opportunities. Finance management focuses on the handling of monetary resources and the financial health of the organization, and stakeholder engagement is concerned with involving various stakeholders in decision-making processes, rather than specifically dealing with uncertainties related to risk and opportunity. Thus, the selection of "Risk and opportunity management" is directly aligned with the definition provided in the question.